The New Drugs to Treat Hypertension Essay example - 809 Words

The New Drugs to Treat Hypertension The purpose of this report is two discuss the Pharmacodynamics, pharmacokinetics, proposed benefits, research method, results of research, and possible-nursing implications of newly approved drugs for the treatment of hypertension. These drugs include Atacand HCT and Diltiazem HCL. All newly approved drugs from the FDA are either new drugs or new formulations of older drugs. The information contained in this report was derived from various web pages and online search engines. Pharmacokinetics: Atacand HCT (Candesartan celexetil) Candesartan is quickly and completely bioactivated by hydrolysis during the absorption from the GI tract to a angiotensin II receptor antagonist (www.rxlist.com).†¦show more content†¦In a 12 week study of diabetic type II patients (n=161) their where no changes in the level of HbA1C (www.rxlist.com). Proposed benefits of drug: Atacand HCT Atacand HCT (Candesartan celexetil-hydrochlorothiazide) was developed for patients who were unsuccessfully treated with single antihypertensive agents. The proposed benefit is elicited by the drugs action on angiotensin II receptor antagonists, the agent that causes vasoconstriction. Additionally the second ingredient hydrochlorothiazide a diuretic reduces blood pressure by improving the kidneys ability to eliminate salt and fluid from the body (www.centerwatch.com). Research method: Atacand HCT They were five double blind, placebo controlled trials for Candesartan celexetil hydrochlorothiazide, which were eight weeks to twelve weeks in duration. The combined study sample consisted of 3,037 hypertensive patients and dosage ranged from 2 to 32 mg Candesartan celexetil and from 6.25 to 25 mg hydrochlorothiazide administered once daily in several combinations (www.centerwatch.com). Results of drug research: Atacand HCT The antihypertensive effects of Atacand was similar in men and women in patients older and younger than 65 (www.rxlist.com). Atacand HCT or the combination (Candesartan celexetil and hydrochlorothiazide) resulted in placebo adjusted decreases in sitting systolic and diastolic bloodShow MoreRelatedPrescription Drugs And The Competitive Market Offers A Starting Point Allusion861 Words   |  4 PagesPrescription drugs in the competitive market offers a starting point allusion, which certain characteristics of medications and healthcare goods and services can be compared to unique goods and services. According to Carter, A, Pharm D Healthline.com say’s â€Å"By not taking care of your diabetes may damage your heart, kidneys, nervous system, and your eyes†. Such as, eating foods with a high content of sugar will extremely increase your blood sugar, or not taking medication to treat diabetes. 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